Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Do not take any other medicine unless prescribed or approved by your doctor . When you are taking metformin, it is especially important that your health care professional know if you are taking any of the following: * Alcohol Small amounts of alcohol taken with meals do not usually cause a problem; however, either larger amounts of alcohol taken for a long time or a large amount of alcohol taken in one sitting without food can increase the effect of metformin. This can keep the blood sugar low for a longer period of time than normal * Amiloride (e.g., Midamor) or * Calcium channel blocking agents (amlodipine [e.g., Norvasc], bepridil [e.g., Bepadin], diltiazem [e.g., Cardizem], felodipine [e.g., Plendil], flunarizine [e.g., Sibelium], isradipine [e.g., DynaCirc], nicardipine [e.g., Cardene], nifedipine [e.g., Procardia], nimodipine [e.g., Nimotop], verapamil [e.g., Calan]) or * Cimetidine (e.g., Tagamet) or * Digoxin (heart medicine) or * Furosemide (e.g., Lasix) or * Morphine (e.g., M S Contin) or * Procainamide (e.g., Pronestyl) or * Quinidine (e.g., Quinidex) or * Quinine (malaria medicine) or * Ranitidine (e.g., Zantac) or * Triamterene (e.g., Dyrenium) or * Trimethoprim (e.g., Proloprim) or * Vancomycin (e.g., Vancocin)Use with metformin may cause high blood levels of metformin, which may increase the chance of low blood sugar or side effects.
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